2XWL

Crystal structure of IspD from Mycobacterium smegmatis in complex with CTP and Mg

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE	polymer	223	22667.9	2	UniProt (A0R560) Pfam (PF01128) In PDB	MYCOBACTERIUM SMEGMATIS	4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL SYNTHASE, MEP CYTIDYLYL TRANSFERASE, CDP-ME SYNTHETASE, ISPD
2	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	A, B	CYTIDINE-5'-TRIPHOSPHATE	non-polymer		483.2	2	Chemie (CTP)
4		water	water		18.0	470	Chemie (HOH)

Sequence modifications

A, B: 1 - 219 (UniProt: A0R560)

PDB	External Database	Details
His 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	45335.7
Non-Polymers*	Number of molecules	4
	Total formula weight	1014.9
All*	Total formula weight	46350.6

*Water molecules are not included.