2XU1
CATHEPSIN L WITH A NITRILE INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | CATHEPSIN L1 | polymer | 220 | 24161.7 | 4 | UniProt (P07711) Pfam (PF00112) In PDB | HOMO SAPIENS (HUMAN) | MAJOR EXCRETED PROTEIN, MEP |
| 2 | A, B, C, D | (2S,4R)-1-[1-(4-chlorophenyl)cyclopropyl]carbonyl-4-(2-chlorophenyl)sulfonyl-N-[1-(iminomethyl)cyclopropyl]pyrrolidine-2-carboxamide | non-polymer | 534.5 | 4 | Chemie (424) | |||
| 3 | water | water | 18.0 | 720 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 220 (UniProt: P07711)
| PDB | External Database | Details |
|---|---|---|
| Ala 110 | Thr 223 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 96646.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2137.8 | |
| All* | Total formula weight | 98784.5 |
