Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008234 | molecular_function | cysteine-type peptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE 424 A 1221 |
| Chain | Residue |
| A | GLN19 |
| A | LEU69 |
| A | MET70 |
| A | ALA135 |
| A | MET161 |
| A | ASP162 |
| A | HIS163 |
| A | GLY164 |
| A | ALA214 |
| A | HOH2094 |
| A | HOH2211 |
| A | GLY23 |
| A | SER24 |
| A | CYS25 |
| A | TRP26 |
| A | GLY61 |
| A | GLU63 |
| A | GLY67 |
| A | GLY68 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 424 B 1221 |
| Chain | Residue |
| B | GLN19 |
| B | GLY23 |
| B | SER24 |
| B | CYS25 |
| B | TRP26 |
| B | GLY61 |
| B | GLY67 |
| B | GLY68 |
| B | LEU69 |
| B | MET70 |
| B | ALA135 |
| B | MET161 |
| B | ASP162 |
| B | HIS163 |
| B | GLY164 |
| B | ALA214 |
| B | HOH2219 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 424 C 1221 |
| Chain | Residue |
| C | GLN19 |
| C | GLY23 |
| C | SER24 |
| C | CYS25 |
| C | TRP26 |
| C | GLY61 |
| C | GLY67 |
| C | GLY68 |
| C | LEU69 |
| C | MET70 |
| C | ALA135 |
| C | MET161 |
| C | ASP162 |
| C | HIS163 |
| C | GLY164 |
| C | ALA214 |
| C | HOH2058 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 424 D 1221 |
| Chain | Residue |
| D | GLN19 |
| D | GLY23 |
| D | SER24 |
| D | CYS25 |
| D | TRP26 |
| D | GLY61 |
| D | GLY67 |
| D | GLY68 |
| D | LEU69 |
| D | MET70 |
| D | ALA135 |
| D | MET161 |
| D | ASP162 |
| D | HIS163 |
| D | GLY164 |
| D | ALA214 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGqCGSCWAfSA |
| Chain | Residue | Details |
| A | GLN19-ALA30 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. MDHGVLVVGYG |
| Chain | Residue | Details |
| A | MET161-GLY171 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWLvKNSWgeeWGmgGYVkM |
| Chain | Residue | Details |
| A | TYR182-MET201 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | CYS25 | |
| B | CYS25 | |
| C | CYS25 | |
| D | CYS25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | HIS163 | |
| A | ASN187 | |
| B | HIS163 | |
| B | ASN187 | |
| C | HIS163 | |
| C | ASN187 | |
| D | HIS163 | |
| D | ASN187 | |
| Chain | Residue | Details |
| A | GLU9 | |
| A | ASP160 | |
| A | ASP162 | |
| B | GLU9 | |
| B | GLU50 | |
| B | ASP71 | |
| B | GLU86 | |
| B | GLU92 | |
| B | GLU96 | |
| B | ASP114 | |
| B | ASP137 | |
| A | GLU50 | |
| B | HIS140 | |
| B | ASP160 | |
| B | ASP162 | |
| C | GLU9 | |
| C | GLU50 | |
| C | ASP71 | |
| C | GLU86 | |
| C | GLU92 | |
| C | GLU96 | |
| C | ASP114 | |
| A | ASP71 | |
| C | ASP137 | |
| C | HIS140 | |
| C | ASP160 | |
| C | ASP162 | |
| D | GLU9 | |
| D | GLU50 | |
| D | ASP71 | |
| D | GLU86 | |
| D | GLU92 | |
| D | GLU96 | |
| A | GLU86 | |
| D | ASP114 | |
| D | ASP137 | |
| D | HIS140 | |
| D | ASP160 | |
| D | ASP162 | |
| A | GLU92 | |
| A | GLU96 | |
| A | ASP114 | |
| A | ASP137 | |
| A | HIS140 | |
| Chain | Residue | Details |
| A | ASN108 | |
| B | ASN108 | |
| C | ASN108 | |
| D | ASN108 | |
