2XSZ

The dodecameric human RuvBL1:RuvBL2 complex with truncated domains II

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	RUVB-LIKE 1	polymer	367	40944.6	3	UniProt (Q9Y265) Pfam (PF06068) Pfam (PF17856) In PDB	HOMO SAPIENS (HUMAN)	RUVBL1,49 KDA TATA BOX-BINDING PROTEIN-INTERACTING PROTEIN, 49 KDA TBP-INTERACTING PROTEIN, TIP49A, PONTIN 52,NUCLEAR MATRIX PROTEIN 238,NMP 238,54 KDA ERYTHROCYTE CYTOSOLIC PROTEIN, ECP-54, TIP60-ASSOCIATED PROTEIN 54-ALPHA, TAP54-ALPHA, INO80 COMPLEX SUBUNIT H
2	D, E, F	RUVB-LIKE 2	polymer	378	42474.4	3	UniProt (Q9Y230) Pfam (PF06068) Pfam (PF17856) In PDB	HOMO SAPIENS (HUMAN)	RUVBL2,48 KDA TATA BOX-BINDING PROTEIN-INTERACTING PROTEIN, 48 KDA TBP-INTERACTING PROTEIN, TIP49B, REPRESSING PONTIN 52,REPTIN 52,51 KDA ERYTHROCYTE CYTOSOLIC PROTEIN, ECP-51, TIP60-ASSOCIATED PROTEIN 54-BETA, TAP54-BETA, INO80 COMPLEX SUBUNIT J
3	A, B, C, D, E...	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	6	Chemie (ATP)

Sequence modifications

A, B, C: 16 - 140 (UniProt: Q9Y265)

PDB	External Database	Details
Mse 1	-	expression tag
Val 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Leu 9	-	expression tag
Leu 10	-	expression tag
Val 11	-	expression tag
Pro 12	-	expression tag
Arg 13	-	expression tag
Gly 14	-	expression tag
Ser 15	-	expression tag

A, B, C: 145 - 367 (UniProt: Q9Y265)
A, B, C: 141 - 144 (PDB: 2XSZ)
D, E, F: 17 - 148 (UniProt: Q9Y230)

PDB	External Database	Details
Mse 1	-	expression tag
Asp 2	-	expression tag
Tyr 3	-	expression tag
Lys 4	-	expression tag
Asp 5	-	expression tag
Asp 6	-	expression tag
Asp 7	-	expression tag
Asp 8	-	expression tag
Lys 9	-	expression tag
Glu 10	-	expression tag
Asn 11	-	expression tag
Leu 12	-	expression tag
Tyr 13	-	expression tag
Phe 14	-	expression tag
Gln 15	-	expression tag
Gly 16	-	expression tag

D, E, F: 153 - 378 (UniProt: Q9Y230)
D, E, F: 149 - 152 (PDB: 2XSZ)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	250256.8
Non-Polymers*	Number of molecules	6
	Total formula weight	3043.1
All*	Total formula weight	253299.9

*Water molecules are not included.