2XSZ
The dodecameric human RuvBL1:RuvBL2 complex with truncated domains II
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| E | 0016887 | molecular_function | ATP hydrolysis activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| F | 0016887 | molecular_function | ATP hydrolysis activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ATP A 501 |
| Chain | Residue |
| A | SER31 |
| A | LYS90 |
| A | THR91 |
| A | ALA92 |
| A | TYR277 |
| A | ILE285 |
| A | LEU314 |
| A | ARG315 |
| F | ASP267 |
| A | HIS32 |
| A | HIS34 |
| A | GLY52 |
| A | LEU53 |
| A | VAL54 |
| A | GLY87 |
| A | THR88 |
| A | GLY89 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ATP B 501 |
| Chain | Residue |
| B | SER31 |
| B | HIS32 |
| B | HIS34 |
| B | GLY52 |
| B | LEU53 |
| B | VAL54 |
| B | GLY87 |
| B | THR88 |
| B | GLY89 |
| B | LYS90 |
| B | THR91 |
| B | ALA92 |
| B | TYR277 |
| B | ILE285 |
| B | LEU314 |
| B | ARG315 |
| D | ASP267 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ATP C 501 |
| Chain | Residue |
| C | SER31 |
| C | HIS32 |
| C | HIS34 |
| C | GLY52 |
| C | LEU53 |
| C | VAL54 |
| C | GLY87 |
| C | THR88 |
| C | GLY89 |
| C | LYS90 |
| C | THR91 |
| C | ALA92 |
| C | TYR277 |
| C | ILE285 |
| C | LEU314 |
| C | ARG315 |
| E | ASP267 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ATP D 501 |
| Chain | Residue |
| A | ASP267 |
| D | ALA39 |
| D | HIS40 |
| D | HIS42 |
| D | ILE43 |
| D | GLY60 |
| D | MSE61 |
| D | VAL62 |
| D | GLY95 |
| D | THR96 |
| D | GLY97 |
| D | LYS98 |
| D | THR99 |
| D | ALA100 |
| D | ASP214 |
| D | TYR277 |
| D | ILE285 |
| D | LEU314 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ATP E 501 |
| Chain | Residue |
| E | ALA39 |
| E | HIS40 |
| E | HIS42 |
| E | ILE43 |
| E | GLY60 |
| E | MSE61 |
| E | VAL62 |
| E | GLY95 |
| E | THR96 |
| E | GLY97 |
| E | LYS98 |
| E | THR99 |
| E | ALA100 |
| E | ASP214 |
| E | TYR277 |
| E | ILE285 |
| E | LEU314 |
| site_id | AC6 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ATP F 501 |
| Chain | Residue |
| F | THR99 |
| F | ALA100 |
| F | ASP214 |
| F | TYR277 |
| F | ILE285 |
| F | LEU314 |
| C | ASP267 |
| F | ALA39 |
| F | HIS40 |
| F | HIS42 |
| F | ILE43 |
| F | GLY60 |
| F | MSE61 |
| F | VAL62 |
| F | GLN64 |
| F | GLY95 |
| F | THR96 |
| F | GLY97 |
| F | LYS98 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: |
| Chain | Residue | Details |
| D | GLY92 | |
| E | GLY92 | |
| F | GLY92 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: N-acetylalanine => ECO:0000269|Ref.14, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712 |
| Chain | Residue | Details |
| D | ALA17 | |
| E | ALA17 | |
| F | ALA17 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| D | SER352 | |
| E | SER352 | |
| F | SER352 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| D | LYS24 | |
| F | LYS359 | |
| F | LYS371 | |
| A | LYS356 | |
| D | LYS359 | |
| D | LYS371 | |
| E | LYS24 | |
| C | LYS356 | |
| E | LYS359 | |
| E | LYS371 | |
| F | LYS24 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | ILE239 | |
| B | ILE239 | |
| C | ILE239 |
