2XSS

Crystal structure of GAFb from the human phosphodiesterase 5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	CGMP-SPECIFIC 3', 5'-CYCLIC PHOSPHODIESTERASE	polymer	181	20673.6	2	UniProt (O76074) Pfam (PF01590) In PDB	HOMO SAPIENS (HUMAN)	CGMP-BINDING CGMP-SPECIFIC PHOSPHODIESTERASE, CGB-PDE

Sequence modifications

A, B: 346 - 509 (UniProt: O76074)

PDB	External Database	Details
Met 330	-	expression tag
Ala 331	-	expression tag
Ser 332	-	expression tag
Trp 333	-	expression tag
Ser 334	-	expression tag
His 335	-	expression tag
Pro 336	-	expression tag
Gln 337	-	expression tag
Phe 338	-	expression tag
Glu 339	-	expression tag
Lys 340	-	expression tag
Gly 341	-	expression tag
Ala 342	-	expression tag
Glu 343	-	expression tag
Thr 344	-	expression tag
Ala 345	-	expression tag
Ala 510	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	41347.2
All*	Total formula weight	41347.2

*Water molecules are not included.