2XRP
Human Doublecortin N-DC Repeat (1MJD) and Mammalian Tubulin (1JFF and 3HKE) Docked into the 8-Angstrom Cryo-EM Map of Doublecortin- Stabilised Microtubules
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G | TUBULIN BETA-2B CHAIN | polymer | 445 | 49907.8 | 4 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) In PDB | BOS TAURUS (CATTLE) | TUBULIN BETA CHAIN |
| 2 | B, D, F, H | TUBULIN ALPHA-1D CHAIN | polymer | 452 | 50236.4 | 4 | UniProt (Q2HJ86) Pfam (PF00091) Pfam (PF03953) In PDB | BOS TAURUS (CATTLE) | TUBULIN ALPHA CHAIN |
| 3 | I | NEURONAL MIGRATION PROTEIN DOUBLECORTIN | polymer | 95 | 11029.4 | 1 | UniProt (O43602) Pfam (PF03607) In PDB | HOMO SAPIENS (HUMAN) | DOUBLECORTIN, LISSENCEPHALIN-X, LIS-X, DOUBLIN |
| 4 | A, C, E, G | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 4 | Chemie (GDP) | |||
| 5 | B, D, F, H | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 4 | Chemie (GTP) |
Sequence modifications
A, C, E, G: 1 - 455 (UniProt: Q6B856)
B, D, F, H: 1 - 449 (UniProt: Q2HJ86)
| PDB | External Database | Details |
|---|---|---|
| Val 172 | Met 170 | conflict |
| Val 318 | Ile 316 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ile 7 | Val 7 | conflict |
| Ile 114 | Leu 114 | conflict |
| Ser 136 | Leu 136 | conflict |
| Glu 358 | Gln 358 | conflict |
| Val 437 | Met 437 | conflict |
| Glu 450 | Asp 450 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 411605.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3865.5 | |
| All* | Total formula weight | 415471.4 |
