2XPX

Crystal structure of BHRF1:Bak BH3 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	APOPTOSIS REGULATOR BHRF1	polymer	173	19848.4	1	UniProt (P03182) Pfam (PF00452) In PDB	HUMAN HERPESVIRUS 4	BHRF1, EARLY ANTIGEN PROTEIN R, EA-R, NUCLEAR ANTIGEN
2	B	BCL-2 HOMOLOGOUS ANTAGONIST/KILLER	polymer	26	2882.2	1	UniProt (Q16611) In PDB	HOMO SAPIENS (HUMAN)	BAK, APOPTOSIS REGULATOR BAK, BCL-2-LIKE PROTEIN 7, BCL2-L-7
3	A	NITRATE ION	non-polymer		62.0	4	Chemie (NO3)
4	A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5		water	water		18.0	73	Chemie (HOH)

Sequence modifications

A: 1 - 160 (UniProt: P03182)

PDB	External Database	Details
Met -12	-	expression tag
Gly -11	-	expression tag
Ser -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Ser -3	-	expression tag
Gln -2	-	expression tag
Asp -1	-	expression tag
Pro 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	22730.5
Non-Polymers*	Number of molecules	6
	Total formula weight	372.2
All*	Total formula weight	23102.7

*Water molecules are not included.