2XKW
LIGAND BINDING DOMAIN OF HUMAN PPAR-GAMMA IN COMPLEX WITH THE AGONIST PIOGLITAZONE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA | polymer | 274 | 31321.4 | 2 | UniProt (P37231) Pfam (PF00104) | HOMO SAPIENS (HUMAN) | PPAR-GAMMA, NUCLEAR RECEPTOR SUBFAMILY 1 GROUP C MEMBER 3 |
| 2 | C, E (A, B) | (5R)-5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione | non-polymer | 356.4 | 2 | Chemie (P1B) | |||
| 3 | D (A) | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | non-polymer | 354.4 | 1 | Chemie (PE4) | |||
| 4 | F (B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62642.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1305.6 | |
| All* | Total formula weight | 63948.4 |
