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2XJD

Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with inorganic phosphate and deoxyadenosine triphosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
CYTOSOLIC PURINE 5'-NUCLEOTIDASEpolymer55463956.81UniProt (P49902)
Pfam (PF05761)
HOMO SAPIENS (HUMAN)CYTOSOLIC 5'-NUCLEOTIDASE II
2B
(A)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
3C, D, E, F, G...
(A)
GLYCEROLnon-polymer92.16Chemie (GOL)
4I
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
5J, K
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6L
(A)
waterwater18.0458Chemie (HOH)
Sequence modifications
A: 1 - 536 (UniProt: P49902)
PDBExternal DatabaseDetails
Gly -17-expression tag
Ser -16-expression tag
Ser -15-expression tag
His -14-expression tag
His -13-expression tag
His -12-expression tag
His -11-expression tag
His -10-expression tag
His -9-expression tag
Ser -8-expression tag
Ser -7-expression tag
Gly -6-expression tag
Leu -5-expression tag
Val -4-expression tag
Pro -3-expression tag
Arg -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Asn 52Asp 52engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight63956.8
Non-Polymers*Number of molecules10
Total formula weight1203.3
All*Total formula weight65160.1
*Water molecules are not included.

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PDB entries from 2025-07-16

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