2XJD

Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with inorganic phosphate and deoxyadenosine triphosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CYTOSOLIC PURINE 5'-NUCLEOTIDASE	polymer	554	63956.8	1	UniProt (P49902) Pfam (PF05761) In PDB	HOMO SAPIENS (HUMAN)	CYTOSOLIC 5'-NUCLEOTIDASE II
2	A	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	1	Chemie (ATP)
3	A	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
4	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
5	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6		water	water		18.0	458	Chemie (HOH)

Sequence modifications

A: 1 - 536 (UniProt: P49902)

PDB	External Database	Details
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Asn 52	Asp 52	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	63956.8
Non-Polymers*	Number of molecules	10
	Total formula weight	1203.3
All*	Total formula weight	65160.1

*Water molecules are not included.