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2XJC

Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with guanosine monophosphate and diadenosine tetraphosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACYTOSOLIC PURINE 5'-NUCLEOTIDASEpolymer55463956.81UniProt (P49902)
Pfam (PF05761)
In PDB
HOMO SAPIENS (HUMAN)CYTOSOLIC 5'-NUCLEOTIDASE II
2AGUANOSINE-5'-MONOPHOSPHATEnon-polymer363.21Chemie (5GP)
3ABIS(ADENOSINE)-5'-TETRAPHOSPHATEnon-polymer836.41Chemie (B4P)
4AGLYCEROLnon-polymer92.18Chemie (GOL)
5AMAGNESIUM IONnon-polymer24.31Chemie (MG)
6waterwater18.0394Chemie (HOH)
Sequence modifications
A: 1 - 536 (UniProt: P49902)
PDBExternal DatabaseDetails
Gly -17-expression tag
Ser -16-expression tag
Ser -15-expression tag
His -14-expression tag
His -13-expression tag
His -12-expression tag
His -11-expression tag
His -10-expression tag
His -9-expression tag
Ser -8-expression tag
Ser -7-expression tag
Gly -6-expression tag
Leu -5-expression tag
Val -4-expression tag
Pro -3-expression tag
Arg -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Asn 52Asp 52engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight63956.8
Non-Polymers*Number of molecules11
Total formula weight1960.7
All*Total formula weight65917.4
*Water molecules are not included.

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PDB entries from 2024-07-31

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