Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

2XFH

Structure of cytochrome P450 EryK cocrystallized with inhibitor clotrimazole.

Replaces:  2VRV
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ERYTHROMYCIN B/D C-12 HYDROXYLASEpolymer41145347.01UniProt (P48635)
Pfam (PF00067)
SACCHAROPOLYSPORA ERYTHRAEACYTOCROME P450 CYP113A1, CYTOCHROME P450 113A1
2B
(A)
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.51Chemie (HEM)
3C, D
(A)
1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLEnon-polymer344.82Chemie (CL6)
4E
(A)
DIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
5F
(A)
waterwater18.0388Chemie (HOH)
Sequence modifications
A: 16 - 411 (UniProt: P48635)
PDBExternal DatabaseDetails
Met 1-expression tag
Phe 2-expression tag
Ala 3-expression tag
Asp 4-expression tag
Val 5-expression tag
Glu 6-expression tag
Thr 7-expression tag
Thr 8-expression tag
Cys 9-expression tag
Cys 10-expression tag
Ala 11-expression tag
Arg 12-expression tag
Arg 13-expression tag
Thr 14-expression tag
Leu 15-expression tag
Leu 344Phe 330engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight45347.0
Non-Polymers*Number of molecules4
Total formula weight1384.3
All*Total formula weight46731.3
*Water molecules are not included.

242500

PDB entries from 2025-10-01

PDB statisticsPDBj update infoContact PDBjnumon