2XE0
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | I-CREI V2V3 VARIANT | polymer | 152 | 17068.6 | 1 | CHLAMYDOMONAS REINHARDTII | ||
2 | B | I-CREI V2V3 VARIANT | polymer | 152 | 16999.4 | 1 | CHLAMYDOMONAS REINHARDTII | ||
3 | C | 24MER DNA | polymer | 24 | 7320.7 | 1 | HOMO SAPIENS | 5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP *AP*CP*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3' | |
4 | D | 24MER DNA | polymer | 24 | 7418.8 | 1 | HOMO SAPIENS | 5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*CP CP*TP*GP*AP*GP*AP*AP*CP*AP*A)-3' | |
5 | A, B | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
6 | B | S-1,2-PROPANEDIOL | non-polymer | 76.1 | 1 | Chemie (PGO) | |||
7 | C, D | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
8 | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 48807.5 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 385.2 | |
All* | Total formula weight | 49192.7 |