2XCV

Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with inosine monophosphate and 2,3-bisphosphoglycerate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CYTOSOLIC PURINE 5'-NUCLEOTIDASE	polymer	554	63956.8	1	UniProt (P49902) Pfam (PF05761) In PDB	HOMO SAPIENS (HUMAN)	CYTOSOLIC 5'-NUCLEOTIDASE II
2	A	(2R)-2,3-diphosphoglyceric acid	non-polymer		266.0	1	Chemie (DG2)
3	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	A	INOSINIC ACID	non-polymer		348.2	1	Chemie (IMP)
5	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
6		water	water		18.0	258	Chemie (HOH)

Sequence modifications

A: 1 - 536 (UniProt: P49902)

PDB	External Database	Details
Gly -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
Leu -5	-	expression tag
Val -4	-	expression tag
Pro -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Asn 52	Asp 52	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	63956.8
Non-Polymers*	Number of molecules	4
	Total formula weight	730.6
All*	Total formula weight	64687.4

*Water molecules are not included.