2XBN
Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE PALMITOYLTRANSFERASE | polymer | 427 | 46030.6 | 1 | UniProt (Q93UV0) Pfam (PF00155) | SPHINGOMONAS PAUCIMOBILIS | SPT, SPT1 |
| 2 | B (A) | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE | non-polymer | 248.2 | 1 | Chemie (PMP) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
A: 2 - 420 (UniProt: Q93UV0)
| PDB | External Database | Details |
|---|---|---|
| Leu 421 | - | expression tag |
| Glu 422 | - | expression tag |
| His 423 | - | expression tag |
| His 424 | - | expression tag |
| His 425 | - | expression tag |
| His 426 | - | expression tag |
| His 427 | - | expression tag |
| His 428 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 46030.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 272.5 | |
| All* | Total formula weight | 46303.0 |
