2XBK

X-ray structure of the substrate-bound cytochrome P450 PimD - a polyene macrolide antibiotic pimaricin epoxidase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PIMD PROTEIN	polymer	404	44528.8	1	UniProt (Q9EW92) Pfam (PF00067)	STREPTOMYCES NATALENSIS
2	B (A)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	1	Chemie (HEM)
3	C (A)	4,5-DE-EPOXYPIMARICIN	non-polymer		649.7	1	Chemie (XBK)
4	D (A)	water	water		18.0	272	Chemie (HOH)

Sequence modifications

A: 5 - 397 (UniProt: Q9EW92)

PDB	External Database	Details
Met -6	-	expression tag
Arg -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
Gly 4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44528.8
Non-Polymers*	Number of molecules	2
	Total formula weight	1266.2
All*	Total formula weight	45795.0

*Water molecules are not included.