2XBK
X-ray structure of the substrate-bound cytochrome P450 PimD - a polyene macrolide antibiotic pimaricin epoxidase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE HEM A 1398 |
| Chain | Residue |
| A | ARG65 |
| A | VAL239 |
| A | ILE242 |
| A | PRO286 |
| A | ARG288 |
| A | LEU311 |
| A | THR338 |
| A | PHE339 |
| A | GLY340 |
| A | ILE343 |
| A | TRP344 |
| A | HIS98 |
| A | CYS346 |
| A | ILE347 |
| A | GLY348 |
| A | ALA352 |
| A | XBK1399 |
| A | HOH2168 |
| A | HOH2268 |
| A | HOH2269 |
| A | ARG102 |
| A | PHE109 |
| A | LEU154 |
| A | LEU231 |
| A | ALA234 |
| A | GLY235 |
| A | SER238 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE XBK A 1399 |
| Chain | Residue |
| A | ARG65 |
| A | LEU178 |
| A | PHE233 |
| A | SER238 |
| A | SER241 |
| A | ARG279 |
| A | SER283 |
| A | VAL284 |
| A | SER387 |
| A | GLY388 |
| A | GLY389 |
| A | HEM1398 |
| A | HOH2168 |
| A | HOH2261 |
| A | HOH2270 |
| A | HOH2271 |
| A | HOH2272 |
