2X9E
HUMAN MPS1 IN COMPLEX WITH NMS-P715
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DUAL SPECIFICITY PROTEIN KINASE TTK | polymer | 317 | 36239.7 | 1 | UniProt (P33981) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | MPS1, PHOSPHOTYROSINE PICKED THREONINE-PROTEIN KINASE, PYT |
| 2 | B (A) | N-(2,6-DIETHYLPHENYL)-1-METHYL-8-({4-[(1-METHYLPIPERIDIN-4-YL)CARBAMOYL]-2-(TRIFLUOROMETHOXY)PHENYL}AMINO)-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE | non-polymer | 676.7 | 1 | Chemie (SVE) | |||
| 3 | C (A) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A: 514 - 828 (UniProt: P33981)
| PDB | External Database | Details |
|---|---|---|
| Gly 512 | - | expression tag |
| Pro 513 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36239.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 676.7 | |
| All* | Total formula weight | 36916.4 |
