2X7E
Crystal structure of human kinesin Eg5 in complex with (R)-fluorastrol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | KINESIN-LIKE PROTEIN KIF11 | polymer | 368 | 41055.6 | 2 | UniProt (P52732) Pfam (PF00225) | HOMO SAPIENS (HUMAN) | KINESIN-RELATED MOTOR PROTEIN EG5, KINESIN-LIKE SPINDLE PROTEIN HKSP, THYROID RECEPTOR-INTERACTING PROTEIN 5, KINESIN-LIKE PROTEIN 1, TRIP-5 |
| 2 | C, F (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 3 | D, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, H (A, B) | (4R)-5-[(S)-(3,4-DIFLUOROPHENYL)(HYDROXY)METHYL]-4-(3-HYDROXYPHENYL)-1,6-DIMETHYL-3,4-DIHYDROPYRIMIDINE-2(1H)-THIONE | non-polymer | 376.4 | 2 | Chemie (X7E) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 336 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82111.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1655.9 | |
| All* | Total formula weight | 83767.0 |
