2X6T

AGME bound to ADP-B-mannose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	ADP-L-GLYCERO-D-MANNO-HEPTOSE-6-EPIMERASE	polymer	357	39891.5	10	UniProt (P67911) Pfam (PF01370) UniProt (by SIFTS) (P67910)	ESCHERICHIA COLI	AGME, ADP-L-GLYCERO-BETA-D-MANNO-HEPTOSE-6-EPIMERASE, ADP-GLYCEROMANNO-HEPTOSE 6-EPIMERASE, ADP-HEP 6-EPIMERASE
2	AA, EA, IA, K, O... (E, F, G, A, B...)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	10	Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (71717786) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (165382010)
3	BA, FA, JA, L, P... (E, F, G, A, B...)	GLYCEROL	non-polymer		92.1	10	Chemie (GOL) PubChem (753)
4	CA, GA, M, MA, Q... (E, F, A, G, B...)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	10	Chemie (ADP)
5	DA, HA, N, NA, R... (E, F, A, G, B...)	beta-D-mannopyranose	non-polymer		180.2	10	Chemie (BMA)
6	KA, LA (G)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL) PubChem (312)
7	AB, BB, CB, DB, EB... (A, B, C, D, E...)	water	water		18.0	1546	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J: -46 - 0 (PDB: 2X6T)
A, B, C, D, E, F, G, H, I, J: 1 - 310 (UniProt: P67911)

PDB	External Database	Details
Phe 140	Tyr 140	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	398915.1
Non-Polymers*	Number of molecules	42
	Total formula weight	14499.5
All*	Total formula weight	413414.6

*Water molecules are not included.