2X5K
Structure of an active site mutant of the D-Erythrose-4-Phosphate Dehydrogenase from E. coli
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | O, P, Q, R | D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE | polymer | 339 | 37299.2 | 4 | UniProt (P0A9B6) Pfam (PF00044) Pfam (PF02800) In PDB | ESCHERICHIA COLI | E4PDH |
| 2 | O, P, R | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 3 | O, P, Q, R | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | O | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | O, P, Q | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 6 | O, P, Q | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 4 | Chemie (PGE) | |||
| 7 | P | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 8 | water | water | 18.0 | 956 | Chemie (HOH) |
Sequence modifications
O, P, Q, R: -1 - 334 (UniProt: P0A9B6)
| PDB | External Database | Details |
|---|---|---|
| Ala 149 | Cys 155 | engineered mutation |
| Ser 153 | Cys 159 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 149196.8 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 1976.4 | |
| All* | Total formula weight | 151173.2 |
