2X4T

Crystal structure of MHC CLass I HLA-A2.1 bound to a Peiodate- cleavable peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2.1	polymer	275	31854.2	2	UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) In PDB	HOMO SAPIENS (HUMAN)	HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN
2	B, E	BETA-2-MICROGLOBULIN	polymer	100	11973.1	2	UniProt (P61769) Pfam (PF07654) In PDB	HOMO SAPIENS (HUMAN)	BETA-2-MICROGLOBULIN FORM PI 5.3
3	C, F	65 KDA PHOSPHOPROTEIN	polymer	9	963.1	2	UniProt (P06725) In PDB	HUMAN HERPESVIRUS 5	LOWER MATRIX PROTEIN PP65,64 KDA MATRIX PHOSPHOPROTEIN
4	A, D	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5	B, E	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
6		water	water		18.0	229	Chemie (HOH)

Sequence modifications

B, E: 0 - 0 (PDB: 2X4T)
B, E: 1 - 99 (UniProt: P61769)
C, F: 1 - 9 (UniProt: P06725)

PDB	External Database	Details
Prw 4	Pro 498	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	89581.0
Non-Polymers*	Number of molecules	5
	Total formula weight	666.8
All*	Total formula weight	90247.8

*Water molecules are not included.