2X4T
Crystal structure of MHC CLass I HLA-A2.1 bound to a Peiodate- cleavable peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2.1 | polymer | 275 | 31854.2 | 2 | UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) | HOMO SAPIENS (HUMAN) | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN |
| 2 | B, E (B, E) | BETA-2-MICROGLOBULIN | polymer | 100 | 11973.1 | 2 | UniProt (P61769) Pfam (PF07654) | HOMO SAPIENS (HUMAN) | BETA-2-MICROGLOBULIN FORM PI 5.3 |
| 3 | C, F (C, F) | 65 KDA PHOSPHOPROTEIN | polymer | 9 | 963.1 | 2 | UniProt (P06725) | HUMAN HERPESVIRUS 5 | LOWER MATRIX PROTEIN PP65,64 KDA MATRIX PHOSPHOPROTEIN |
| 4 | G, I, J (A, D) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | H, K (B, E) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 6 | L, M, N, O, P... (A, B, C, D, E...) | water | water | 18.0 | 229 | Chemie (HOH) |
Sequence modifications
B, E: 0 - 0 (PDB: 2X4T)
B, E: 1 - 99 (UniProt: P61769)
C, F: 1 - 9 (UniProt: P06725)
B, E: 1 - 99 (UniProt: P61769)
C, F: 1 - 9 (UniProt: P06725)
| PDB | External Database | Details |
|---|---|---|
| Prw 4 | Pro 498 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 89581.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 666.8 | |
| All* | Total formula weight | 90247.8 |
