2X4D
Crystal structure of human phospholysine phosphohistidine inorganic pyrophosphate phosphatase LHPP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PHOSPHOLYSINE PHOSPHOHISTIDINE INORGANIC PYROPHOSPHATE PHOSPHATASE | polymer | 271 | 29085.2 | 2 | UniProt (Q9H008) Pfam (PF13344) Pfam (PF13242) | HOMO SAPIENS (HUMAN) | HLHPP |
| 2 | C, G (A, B) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 2 | Chemie (POP) | |||
| 3 | D, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, I (A, B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 5 | F (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 212 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 0 (PDB: 2X4D)
A, B: 1 - 270 (UniProt: Q9H008)
A, B: 1 - 270 (UniProt: Q9H008)
| PDB | External Database | Details |
|---|---|---|
| Arg 94 | Gln 94 | SEE REMARK 999 |
| Ala 160 | Lys 160 | engineered mutation |
| Ala 161 | Glu 161 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58170.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 969.2 | |
| All* | Total formula weight | 59139.6 |
