2WZD
The catalytically active fully closed conformation of human phosphoglycerate kinase K219A mutant in complex with ADP, 3PG and aluminium trifluoride
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PHOSPHOGLYCERATE KINASE 1 | polymer | 417 | 44614.5 | 1 | UniProt (P00558) Pfam (PF00162) | HOMO SAPIENS (HUMAN) | PRIMER RECOGNITION PROTEIN 2, PRP 2, CELL MIGRATION-INDUCING GENE 10 PROTEIN |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 1 | Chemie (AF3) | |||
| 5 | E (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 6 | F (A) | 3-PHOSPHOGLYCERIC ACID | non-polymer | 186.1 | 1 | Chemie (3PG) | |||
| 7 | G (A) | water | water | 18.0 | 466 | Chemie (HOH) |
Sequence modifications
A: 0 - 416 (UniProt: P00558)
| PDB | External Database | Details |
|---|---|---|
| Ala 219 | Lys 220 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44614.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 757.0 | |
| All* | Total formula weight | 45371.5 |
