2WYA

CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL 3-HYDROXY-3-METHYLGLUTARYL- COENZYME A SYNTHASE 2 (HMGCS2)

Replaces:  2V4W

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	HYDROXYMETHYLGLUTARYL-COA SYNTHASE, MITOCHONDRIAL	polymer	460	51316.0	4	UniProt (P54868) Pfam (PF01154) Pfam (PF08540)	HOMO SAPIENS (HUMAN)	HMG-COA SYNTHASE, 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE
2	E, G, H, I (A, B, C, D)	3-HYDROXY-3-METHYLGLUTARYL-COENZYME A	non-polymer		906.6	4	Chemie (HMG)
3	F (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	J, K, L, M (A, B, C, D)	water	water		18.0	1457	Chemie (HOH)

Sequence modifications

A, B, C, D: 49 - 50 (PDB: 2WYA)
A, B, C, D: 51 - 508 (UniProt: P54868)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	205263.9
Non-Polymers*	Number of molecules	5
	Total formula weight	3718.6
All*	Total formula weight	208982.4

*Water molecules are not included.