2WXJ

The crystal structure of the murine class IA PI 3-kinase p110delta in complex with INK654.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM	polymer	940	107823.7	1	UniProt (Q3UDT3) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) UniProt (by SIFTS) (O35904)	MUS MUSCULUS (MOUSE)	PI3-KINASE P110 SUBUNIT DELTA, PTDINS-3-KINASE P110, P110DELTA, PI3K
2	B (A)	N-[6-(4-amino-1-{[2-(4-methylpiperazin-1-yl)quinolin-3-yl]methyl}-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzothiazol-2-yl]acetamide	non-polymer		564.7	1	Chemie (RW3)
3	C (A)	water	water		18.0	49	Chemie (HOH)

Sequence modifications

A: 105 - 105 (PDB: 2WXJ)
A: 106 - 1044 (UniProt: Q3UDT3)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	107823.7
Non-Polymers*	Number of molecules	1
	Total formula weight	564.7
All*	Total formula weight	108388.3

*Water molecules are not included.