2WWK

Crystal structure of the Titin M10-Obscurin like 1 Ig F17R mutant complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	O	OBSCURIN-LIKE PROTEIN 1	polymer	109	11135.6	1	UniProt (O75147) Pfam (PF07679) In PDB	HOMO SAPIENS (HUMAN)
2	T	TITIN	polymer	102	10981.2	1	UniProt (Q8WZ42) Pfam (PF07679) In PDB	HOMO SAPIENS (HUMAN)	CONNECTIN, RHABDOMYOSARCOMA ANTIGEN MU-RMS-40.14
3	O	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	O	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5		water	water		18.0	287	Chemie (HOH)

Sequence modifications

O: 1 - 106 (UniProt: O75147)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
Ser 0	-	expression tag
Arg 17	Phe 17	engineered mutation

T: 1 - 99 (UniProt: Q8WZ42)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	22116.9
Non-Polymers*	Number of molecules	2
	Total formula weight	188.2
All*	Total formula weight	22305.0

*Water molecules are not included.