2WWJ

STRUCTURE OF JMJD2A COMPLEXED WITH INHIBITOR 10A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	LYSINE-SPECIFIC DEMETHYLASE 4A	polymer	348	40533.2	2	UniProt (O75164) Pfam (PF02375) Pfam (PF02373)	Homo sapiens (Human)	JUMONJI DOMAIN CONTAINING PROTEIN 2A, JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3A
2	C, F (A, B)	NICKEL (II) ION	non-polymer		58.7	2	Chemie (NI)
3	D, G (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	E, H (A, B)	O-benzyl-N-(carboxycarbonyl)-D-tyrosine	non-polymer		343.3	2	Chemie (Y28)
5	I, J (A, B)	water	water		18.0	144	Chemie (HOH)

Sequence modifications

A, B: 7 - 353 (UniProt: O75164)
A, B: 354 - 354 (PDB: 2WWJ)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	81066.4
Non-Polymers*	Number of molecules	6
	Total formula weight	934.9
All*	Total formula weight	82001.3

*Water molecules are not included.