2WUZ

X-ray structure of CYP51 from Trypanosoma cruzi in complex with fluconazole in alternative conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	LANOSTEROL 14-ALPHA-DEMETHYLASE, PUTATIVE	polymer	473	54120.8	2	UniProt (Q5I4E1) Pfam (PF00067) UniProt (by SIFTS) (Q7Z1V1) In PDB	TRYPANOSOMA CRUZI	STEROL 14 ALPHA-DEMETHYLASE, CYP51
2	A, B	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	A, B	2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL	non-polymer		306.3	2	Chemie (TPF)
4		water	water		18.0	176	Chemie (HOH)

Sequence modifications

A, B: 15 - 21 (PDB: 2WUZ)
A, B: 482 - 487 (PDB: 2WUZ)
A, B: 22 - 481 (UniProt: Q5I4E1)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	108241.5
Non-Polymers*	Number of molecules	4
	Total formula weight	1845.5
All*	Total formula weight	110087.0

*Water molecules are not included.