2WU7

Crystal Structure of the Human CLK3 in complex with V25

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DUAL SPECIFICITY PROTEIN KINASE CLK3	polymer	381	44790.1	1	UniProt (P49761) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	CDC-LIKE KINASE 3, CDC-LIKE KINASE 3 ISOFORM HCLK3
2	B (A)	ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate	non-polymer		338.2	1	Chemie (V25)
3	C, D, E, F, G (A)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
4	H, I (A)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	J (A)	water	water		18.0	163	Chemie (HOH)

Sequence modifications

A: 104 - 126 (PDB: 2WU7)
A: 127 - 484 (UniProt: P49761)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44790.1
Non-Polymers*	Number of molecules	8
	Total formula weight	889.4
All*	Total formula weight	45679.5

*Water molecules are not included.