2WTX
Insight into the mechanism of enzymatic glycosyltransfer with retention through the synthesis and analysis of bisubstrate glycomimetics of trehalose-6-phosphate synthase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | ALPHA, ALPHA-TREHALOSE-PHOSPHATE SYNTHASE [UDP-FORMING] | polymer | 474 | 53676.0 | 4 | UniProt (P31677) Pfam (PF00982) | ESCHERICHIA COLI | TREHALOSE-6-PHOSPHATE SYNTHASE, UDP-GLUCOSE-GLUCOSEPHOSPHATE GLUCOSYLTRANSFERASE, OSMOREGULATORY TREHALOSE SYNTHESIS PROTEIN A |
| 2 | E, F, G, J, K (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 3 | H, L, N, P (A, B, C, D) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 4 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (60098857) PubChem (57448939) PubChem (3084486) PubChem (91746160) PubChem (6101632) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (6604175) PubChem (11811538) PubChem (12049241) | |||
| 4 | I, M, O, Q (A, B, C, D) | [(1R,2R,3S,4S,5S)-2,3,4-TRIHYDROXY-5-{[(1S,4R,5S,6S)-4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)CYCLOHEX-2-EN-1-YL]AMINO}CYCLOHEXYL]METHYL DIHYDROGEN PHOSPHATE | non-polymer | 415.3 | 4 | Chemie (VDO) PubChem (44629416) PubChem (75059171) | |||
| 5 | R, S, T, U (A, B, C, D) | water | water | 18.0 | 585 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 214703.9 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 3588.3 | |
| All* | Total formula weight | 218292.2 |
