2WTX

Insight into the mechanism of enzymatic glycosyltransfer with retention through the synthesis and analysis of bisubstrate glycomimetics of trehalose-6-phosphate synthase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	ALPHA, ALPHA-TREHALOSE-PHOSPHATE SYNTHASE [UDP-FORMING]	polymer	474	53676.0	4	UniProt (P31677) Pfam (PF00982)	ESCHERICHIA COLI	TREHALOSE-6-PHOSPHATE SYNTHASE, UDP-GLUCOSE-GLUCOSEPHOSPHATE GLUCOSYLTRANSFERASE, OSMOREGULATORY TREHALOSE SYNTHESIS PROTEIN A
2	E, F, G, J, K (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
3	H, L, N, P (A, B, C, D)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	4	Chemie (UDP)
4	I, M, O, Q (A, B, C, D)	[(1R,2R,3S,4S,5S)-2,3,4-TRIHYDROXY-5-{[(1S,4R,5S,6S)-4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)CYCLOHEX-2-EN-1-YL]AMINO}CYCLOHEXYL]METHYL DIHYDROGEN PHOSPHATE	non-polymer		415.3	4	Chemie (VDO)
5	R, S, T, U (A, B, C, D)	water	water		18.0	585	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	214703.9
Non-Polymers*	Number of molecules	13
	Total formula weight	3588.3
All*	Total formula weight	218292.2

*Water molecules are not included.