2WTJ

CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	CHECKPOINT KINASE 2	polymer	329	37111.8	1	UniProt (Q9HBS5) Pfam (PF00069) UniProt (by SIFTS) (O96017) In PDB	HOMO SAPIENS (HUMAN)
2	A	2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)-N-[2-(DIMETHYLAMINO)ETHYL]PYRIDINE-3-CARBOXAMIDE	non-polymer		348.4	1	Chemie (WTJ)
3	A	NITRATE ION	non-polymer		62.0	2	Chemie (NO3)
4	A	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
5		water	water		18.0	248	Chemie (HOH)

Sequence modifications

A: 203 - 221 (PDB: 2WTJ)
A: 222 - 531 (UniProt: Q9HBS5)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	37111.8
Non-Polymers*	Number of molecules	7
	Total formula weight	720.7
All*	Total formula weight	37832.5

*Water molecules are not included.