2WTI
CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CHECKPOINT KINASE 2 | polymer | 329 | 37111.8 | 1 | UniProt (Q9HBS5) Pfam (PF00069) UniProt (by SIFTS) (O96017) | HOMO SAPIENS (HUMAN) | |
| 2 | B (A) | 4-[2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)PYRIDIN-3-YL]BENZAMIDE | non-polymer | 353.4 | 1 | Chemie (WTI) | |||
| 3 | C, D (A) | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
| 4 | E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | G (A) | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37111.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 601.5 | |
| All* | Total formula weight | 37713.4 |
