2WSQ

MonoTIM mutant RMM0-1, dimeric form.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	TRIOSE PHOSPHATE ISOMERASE, GLYCOSOMAL	polymer	242	25973.7	4	UniProt (P04789) Pfam (PF00121)	TRYPANOSOMA BRUCEI BRUCEI	TIM, TRIOSE-PHOSPHATE ISOMERASE, MONOTIM MUTANT RMM0-1
2	E, F, G, H, I... (A, B, C, D)	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
3	M, N, O, P (A, B, C, D)	water	water		18.0	1553	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 67 (UniProt: P04789)

PDB	External Database	Details
Pro 43	Ser 43	engineered mutation
Ser 44	Thr 44	engineered mutation

A, B, C, D: 84 - 250 (UniProt: P04789)

PDB	External Database	Details
Thr 186	Ala 186	engineered mutation

A, B, C, D: 68 - 83 (PDB: 2WSQ)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	103894.6
Non-Polymers*	Number of molecules	8
	Total formula weight	768.5
All*	Total formula weight	104663.1

*Water molecules are not included.