2WSA

Crystal Structure of Leishmania major N-myristoyltransferase (NMT) with bound myristoyl-CoA and a pyrazole sulphonamide ligand (DDD85646)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE	polymer	438	50527.2	1	UniProt (Q4Q5S8) Pfam (PF01233) Pfam (PF02799)	LEISHMANIA MAJOR	N-MYRISTOYL TRANSFERASE
2	B (A)	TETRADECANOYL-COA	non-polymer		977.9	1	Chemie (MYA)
3	C (A)	2,6-dichloro-4-(2-piperazin-1-ylpyridin-4-yl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide	non-polymer		495.4	1	Chemie (646)
4	D (A)	water	water		18.0	556	Chemie (HOH)

Sequence modifications

A: -16 - 4 (PDB: 2WSA)
A: 5 - 421 (UniProt: Q4Q5S8)

PDB	External Database	Details
Asp 27	Thr 27	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	50527.2
Non-Polymers*	Number of molecules	2
	Total formula weight	1473.3
All*	Total formula weight	52000.6

*Water molecules are not included.