2WRM
Identification of Novel Allosteric Inhibitors of Hepatitis C Virus NS5B Polymerase Thumb Domain (Site II) by Structure-Based Design
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA-DIRECTED RNA POLYMERASE | polymer | 536 | 59641.5 | 1 | UniProt (P26663) Pfam (PF00998) | HEPATITIS C VIRUS | P68 |
| 2 | B, C, D (A) | (3R)-3-(4-METHYL-1,3-DIOXO-1,3-DIHYDRO-2H-PYRROLO[3,4-C]QUINOLIN-2-YL)HEXANOIC ACID | non-polymer | 326.3 | 3 | Chemie (QQ3) | |||
| 3 | E (A) | water | water | 18.0 | 629 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 59641.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 979.0 | |
| All* | Total formula weight | 60620.5 |
