2WP6
Trypanosoma brucei trypanothione reductase in complex with 3,4- dihydroquinazoline inhibitor (DDD00071494)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | TRYPANOTHIONE REDUCTASE | polymer | 495 | 53498.0 | 4 | UniProt (Q389T8) Pfam (PF07992) Pfam (PF02852) In PDB | TRYPANOSOMA BRUCEI | |
2 | A, B, C, D | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
3 | A, B, C, D | (4S)-3-BENZYL-6-CHLORO-2-METHYL-4-PHENYL-3,4-DIHYDROQUINAZOLINE | non-polymer | 346.9 | 4 | Chemie (WP6) | |||
4 | A, B, C, D | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
5 | water | water | 18.0 | 915 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 492 (UniProt: Q389T8)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 213991.9 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 4706.9 | |
All* | Total formula weight | 218698.8 |