2WOA

MMP12 complex with a beta hydroxy carboxylic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	MACROPHAGE METALLOELASTASE	polymer	164	18232.4	4	UniProt (P39900) Pfam (PF00413) In PDB	HOMO SAPIENS (HUMAN)	MMP12, MATRIX METALLOPROTEINASE-12, MACROPHAGE ELASTASE, HME, MMP-12, ME
2	A, D, B, C	SULFATE ION	non-polymer		96.1	7	Chemie (SO4)
3	D, A, B, C	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
4	D, A, B, C	CALCIUM ION	non-polymer		40.1	9	Chemie (CA)
5	A, C	(3S)-5-(9H-FLUOREN-2-YL)-3-HYDROXYPENTANOIC ACID	non-polymer		282.3	2	Chemie (576)
6	D, B	N^2^-[(2R)-2-{(1S)-1-[FORMYL(HYDROXY)AMINO]ETHYL}-5-PHENYLPENTANOYL]-N,3-DIMETHYL-L-VALINAMIDE	non-polymer		391.5	2	Chemie (023)
7	D	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
8		water	water		18.0	427	Chemie (HOH)

Sequence modifications

A, B, C, D: 105 - 105 (PDB: 2WOA)
A, B, C, D: 106 - 268 (UniProt: P39900)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	72929.4
Non-Polymers*	Number of molecules	30
	Total formula weight	3088.3
All*	Total formula weight	76017.7

*Water molecules are not included.