2WO8

MMP12 complex with a beta hydroxy carboxylic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	MACROPHAGE METALLOELASTASE	polymer	164	18232.4	4	UniProt (P39900) Pfam (PF00413) In PDB	HOMO SAPIENS (HUMAN)	MATRIX METALLOPROTEINASE-12, MMP12, MACROPHAGE METALLOELASTASE, MACROPHAGE ELASTASE, ME
2	A, B, C, D	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
3	A, B, C, D	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)
4	A, C	(3S)-5-biphenyl-4-yl-3-hydroxypentanoic acid	non-polymer		270.3	2	Chemie (077)
5	D, A, B, C	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
6	B, D	N^2^-[(2R)-2-{(1S)-1-[FORMYL(HYDROXY)AMINO]ETHYL}-5-PHENYLPENTANOYL]-N,3-DIMETHYL-L-VALINAMIDE	non-polymer		391.5	2	Chemie (023)
7	D	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
8		water	water		18.0	537	Chemie (HOH)

Sequence modifications

A, B, C, D: 105 - 105 (PDB: 2WO8)
A, B, C, D: 106 - 268 (UniProt: P39900)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	72929.4
Non-Polymers*	Number of molecules	25
	Total formula weight	2751.9
All*	Total formula weight	75681.3

*Water molecules are not included.