2WO2

Crystal Structure of the EphA4-ephrinB2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	EPHRIN TYPE-A RECEPTOR	polymer	185	21467.2	1	UniProt (P54764) Pfam (PF01404) In PDB	Homo sapiens (Human)	TYROSINE-PROTEIN KINASE RECEPTOR SEK, RECEPTOR PROTEIN-TYROSINE KINASE HEK8, TYROSINE-PROTEIN KINASE TYRO1
2	B	EPHRIN-B2	polymer	153	17506.9	1	UniProt (P52799) Pfam (PF00812) In PDB	Homo sapiens (Human)	EPH-RELATED RECEPTOR TYROSINE KINASE LIGAND 5, LERK-5, HTK LIGAND, HTK-L
3	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
4		water	water		18.0	49	Chemie (HOH)

Sequence modifications

A: 30 - 202 (UniProt: P54764)

PDB	External Database	Details
Glu 27	-	expression tag
Thr 28	-	expression tag
Gly 29	-	expression tag
Arg 203	-	expression tag
Thr 204	-	expression tag
Lys 205	-	expression tag
His 206	-	expression tag
His 207	-	expression tag
His 208	-	expression tag
His 209	-	expression tag
His 210	-	expression tag
His 211	-	expression tag

B: 27 - 167 (UniProt: P52799)

PDB	External Database	Details
Glu 24	-	expression tag
Thr 25	-	expression tag
Gly 26	-	expression tag
Gly 168	-	expression tag
Thr 169	-	expression tag
Lys 170	-	expression tag
His 171	-	expression tag
His 172	-	expression tag
His 173	-	expression tag
His 174	-	expression tag
His 175	-	expression tag
His 176	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	38974.0
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	39195.3

*Water molecules are not included.