2WKY
Crystal structure of the ligand-binding core of GluR5 in complex with the agonist 4-AHCP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1 | polymer | 258 | 29237.6 | 2 | UniProt (P22756) Pfam (PF10613) Pfam (PF00060) | RATTUS NORVEGICUS (RAT) | GLUTAMATE RECEPTOR 5, GLUR-5, GLUR5 |
| 2 | C, D (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 3 | E, F (A, B) | 3-(3-HYDROXY-7,8-DIHYDRO-6H-CYCLOHEPTA[D]ISOXAZOL-4-YL)-L-ALANINE | non-polymer | 238.2 | 2 | Chemie (IBC) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 295 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 116 (UniProt: P22756)
A, B: 119 - 258 (UniProt: P22756)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Gly 34 | Ala 462 | SEE REMARK 999 |
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | linker |
| Thr 118 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58475.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 547.4 | |
| All* | Total formula weight | 59022.5 |
