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2WJY

Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 Orthorhombic form

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
REGULATOR OF NONSENSE TRANSCRIPTS 1polymer80089984.21UniProt (Q92900)
Pfam (PF09416)
Pfam (PF18141)
Pfam (PF13086)
Pfam (PF13087)
HOMO SAPIENS (HUMAN)UPF1, ATP-DEPENDENT HELICASE RENT1, NONSENSE MRNA REDUCING FACTOR 1, UP-FRAMESHIFT SUPPRESSOR 1 HOMOLOG, NORF1, HUPF1
2B, C, D
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
3E, F, G, H, I...
(A)
SULFATE IONnon-polymer96.18Chemie (SO4)
4M
(A)
waterwater18.0254Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight89984.2
Non-Polymers*Number of molecules11
Total formula weight964.7
All*Total formula weight90949.0
*Water molecules are not included.

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PDB entries from 2025-12-24

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