2WI6
Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HEAT SHOCK PROTEIN, HSP90-ALPHA | polymer | 236 | 26601.8 | 1 | UniProt (P07900) Pfam (PF13589) In PDB | HOMO SAPIENS (HUMAN) | HSP 86, RENAL CARCINOMA ANTIGEN NY-REN-38 |
2 | A | 2-AMINO-4-(2,4-DICHLOROPHENYL)-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE | non-polymer | 367.3 | 1 | Chemie (ZZ6) | |||
3 | water | water | 18.0 | 31 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 26601.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 367.3 | |
All* | Total formula weight | 26969.0 |