2WI3
Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HEAT SHOCK PROTEIN, HSP 90-ALPHA | polymer | 236 | 26601.8 | 1 | UniProt (P07900) Pfam (PF13589) | HOMO SAPIENS (HUMAN) | HSP 86, RENAL CARCINOMA ANTIGEN NY-REN-38 |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | 4-METHYL-6-(METHYLSULFANYL)-1,3,5-TRIAZIN-2-AMINE | non-polymer | 156.2 | 1 | Chemie (ZZ3) | |||
| 4 | D (A) | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26601.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 180.5 | |
| All* | Total formula weight | 26782.3 |
