2WI3

Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
AHEAT SHOCK PROTEIN, HSP 90-ALPHApolymer23626601.81
UniProt (P07900)
Pfam (PF02518)
HOMO SAPIENS (HUMAN)@PDBjHSP 86, RENAL CARCINOMA ANTIGEN NY-REN-38
MAGNESIUM IONnon-polymer24.31
4-METHYL-6-(METHYLSULFANYL)-1,3,5-TRIAZIN-2-AMINEnon-polymer156.21
waterwater18.0271

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains1
Total molecular weight26601.8
Non-Polymers*Number of molecules2
Total molecular weight180.5
All*Total molecular weight26782.3
*Water molecules are not included.