2WH6

Crystal structure of anti-apoptotic BHRF1 in complex with the Bim BH3 domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	EARLY ANTIGEN PROTEIN R	polymer	173	19848.4	1	UniProt (P03182) Pfam (PF00452) UniProt (by SIFTS) (P0C6Z1)	Epstein-barr virus strain ag876	NUCLEAR ANTIGEN, EA-R, BHRF1
2	B (B)	BCL-2-LIKE PROTEIN 11	polymer	26	3274.7	1	UniProt (O43521) Pfam (PF08945)	HOMO SAPIENS	BCL2-L-11, BCL2-INTERACTING MEDIATOR OF CELL DEATH, BIM
3	C, D, E, F, G... (A)	BROMIDE ION	non-polymer		79.9	9	Chemie (BR)
4	L, M (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
5	N, O (A, B)	water	water		18.0	115	Chemie (HOH)

Sequence modifications

A: 1 - 160 (UniProt: P03182)

PDB	External Database	Details
Met -12	-	expression tag
Gly -11	-	expression tag
Ser -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Ser -3	-	expression tag
Gln -2	-	expression tag
Asp -1	-	expression tag
Pro 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	23123.1
Non-Polymers*	Number of molecules	11
	Total formula weight	903.3
All*	Total formula weight	24026.4

*Water molecules are not included.