2WGY

Crystal structure of the G243A mutant of CYP130 from M. tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	CYTOCHROME P450 130	polymer	413	45719.6	1	UniProt (Q11062) Pfam (PF00067) UniProt (by SIFTS) (P9WPN5)	MYCOBACTERIUM TUBERCULOSIS	CYP130
2	B (A)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	1	Chemie (HEM)
3	C, D, E, F, G (A)	ISOPROPYL ALCOHOL	non-polymer		60.1	5	Chemie (IPA)
4	H, I, J, K (A)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
5	L (A)	water	water		18.0	323	Chemie (HOH)

Sequence modifications

A: -5 - 1 (PDB: 2WGY)
A: 406 - 407 (PDB: 2WGY)
A: 2 - 405 (UniProt: Q11062)

PDB	External Database	Details
Ala 243	Gly 243	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45719.6
Non-Polymers*	Number of molecules	10
	Total formula weight	1301.2
All*	Total formula weight	47020.8

*Water molecules are not included.