2WGX
HUMAN P53 CORE DOMAIN MUTANT M133L-V203A-Y236F-N239Y-T253I-N268D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | CELLULAR TUMOR ANTIGEN P53 | polymer | 219 | 24586.9 | 2 | UniProt (P04637) Pfam (PF00870) | HOMO SAPIENS (HUMAN) | TUMOR SUPPRESSOR P53, PHOSPHOPROTEIN P53, ANTIGEN NY-CO-13, P53 |
| 2 | C, D (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 455 | Chemie (HOH) |
Sequence modifications
A, B: 94 - 312 (UniProt: P04637)
| PDB | External Database | Details |
|---|---|---|
| Leu 133 | Met 133 | engineered mutation |
| Ala 203 | Val 203 | engineered mutation |
| Phe 236 | Tyr 236 | engineered mutation |
| Tyr 239 | Asn 239 | engineered mutation |
| Ile 253 | Thr 253 | engineered mutation |
| Asp 268 | Asn 268 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49173.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 49304.6 |
