2WEY

Human PDE-papaverine complex obtained by ligand soaking of cross- linked protein crystals

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE	polymer	343	39462.3	2	UniProt (Q9Y233)	HOMO SAPIENS (HUMAN)	PHOSPHODIESTERASE 10A2, PDE10A
2	C, F (A, B)	1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXYISOQUINOLINE	non-polymer		339.4	2	Chemie (EV1)
3	D, G (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	E, H (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	I, J (A, B)	water	water		18.0	23	Chemie (HOH)

Sequence modifications

A, B: 447 - 448 (PDB: 2WEY)
A, B: 449 - 789 (UniProt: Q9Y233)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	78924.6
Non-Polymers*	Number of molecules	6
	Total formula weight	858.2
All*	Total formula weight	79782.8

*Water molecules are not included.