2WEL

Crystal structure of SU6656-bound calcium/calmodulin-dependent protein kinase II delta in complex with calmodulin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II DELTA CHAIN	polymer	327	37006.5	1	UniProt (Q13557) Pfam (PF00069)	HOMO SAPIENS (HUMAN)	CALCIUM CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II DELTA, CAM-KINASE II DELTA CHAIN, CAM KINASE II SUBUNIT DELTA, CAMK-II SUBUNIT DELTA
2	B (D)	CALMODULIN	polymer	150	16939.6	1	UniProt (P62158) Pfam (PF13499) UniProt (by SIFTS) (P0DP23)	HOMO SAPIENS (HUMAN)	CAM
3	C (A)	(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE	non-polymer		371.5	1	Chemie (K88)
4	D, E, F, G, H... (A)	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
5	J, K (A)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
6	L, M, N, O (D)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
7	P, Q (A, D)	water	water		18.0	405	Chemie (HOH)

Sequence modifications

A: -1 - 0 (PDB: 2WEL)
A: 11 - 335 (UniProt: Q13557)
D: -1 - -1 (PDB: 2WEL)
D: 1 - 149 (UniProt: P62158)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53946.1
Non-Polymers*	Number of molecules	13
	Total formula weight	1094.1
All*	Total formula weight	55040.2

*Water molecules are not included.