2WEI

Crystal structure of the kinase domain of Cryptosporidium parvum calcium dependent protein kinase in complex with 3-MB-PP1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	CALMODULIN-DOMAIN PROTEIN KINASE 1, PUTATIVE	polymer	287	33445.4	1	UniProt (A3FQ16) Pfam (PF00069)	CRYPTOSPORIDIUM PARVUM IOWA II	KINASE DOMAIN OF CALCIUM DEPENDENT PROTEIN KINASE 4
2	B (A)	1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	non-polymer		295.4	1	Chemie (VGG)
3	C (A)	water	water		18.0	199	Chemie (HOH)

Sequence modifications

A: 70 - 338 (UniProt: A3FQ16)

PDB	External Database	Details
Met -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Arg -6	-	expression tag
Glu -5	-	expression tag
Asn -4	-	expression tag
Leu -3	-	expression tag
Tyr -2	-	expression tag
Phe -1	-	expression tag
Gln 0	-	expression tag
Glu 339	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33445.4
Non-Polymers*	Number of molecules	1
	Total formula weight	295.4
All*	Total formula weight	33740.8

*Water molecules are not included.